It’s been a year since Martin resigned his medical license, and Louisa is now the one seeing patients out of the surgery for her child counseling practice, while Martin looks after James Henry and four-month-old Mary Elizabeth. When the mother of one of Louisa’s patients presents with serious symptoms but refuses to allow Martin to examine her, he finally admits that he wants to be a doctor again.

The Portwenn surgery has reopened, but between Martin and Louisa sharing the office and a less-than-competent new receptionist, things aren’t running very smoothly. When Louisa’s childhood dream home goes on the market, she jumps at the chance to look for a larger space. The house’s owner is an accident-prone recent widower who seems haunted by his wife’s death—perhaps literally.

While checking on a sick sheep farmer, Doc runs into Stewart James, a patient who used to suffer from delusions that he lived with a giant squirrel. Stewart is now starting a survival course business, and invites Al and PC Penhale to join him in the woods for a test run. When Stewart begins to behave oddly, Al worries he’s having a mental breakdown. Guest Starring Ben Miller (Death in Paradise).

When Martin advises a patient suffering from migraines to stop cold-water swimming, Mrs. Tishell’s attempts to help almost lead to disaster. Martin has his own headaches to deal with when an herbalist sets up shop in the village and then an ex-flame arrives on his doorstep. Meanwhile, Penhale tries to rekindle his romance with Janice. Guest starring Lesley Nicol (Downton Abbey) .